Enhanced apoptosis in retinal pigment epithelium under inflammatory stimuli and oxidative stress

Age-related macular degeneration (AMD) is a neurodegenerative disease that causes irreversible central vision loss in the elderly. Retinal pigment epithelium (RPE) has been found to be a key component in AMD pathogenesis. The Ccl2(−/−)/Cx3cr1(−/−) (DKO) mouse on Crb1(rd8) background is created as an...

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Hlavní autoři: Wang, Yujuan, Shen, Defen, Wang, Vinson M., Yu, Cheng-Rong, Wang, Ren-Xi, Tuo, Jingsheng, Chan, Chi-Chao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469765/
https://ncbi.nlm.nih.gov/pubmed/22911474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-012-0750-1
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