Anti-tumor Activity of Triolimus: A Novel Multi-Drug Loaded Micelle Containing Paclitaxel, Rapamycin and 17-AAG

Triolimus is a first-in-class, multi-drug loaded micelle containing paclitaxel, rapamycin and 17-AAG. In this study, we examine the anti-tumor mechanisms of action, efficacy and toxicity of Triolimus in vitro and in vivo. In vitro cytotoxicity testing of Triolimus was conducted using two aggressive...

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Bibliografiske detaljer
Main Authors: Hasenstein, Jason R., Shin, Ho-Chul, Kasmerchak, Kelsey, Buehler, Darya, Kwon, Glen S., Kozak, Kevin R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469732/
https://ncbi.nlm.nih.gov/pubmed/22896668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0987
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