Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits.

Rabbit livers express two genetically distinct receptors for plasma lipoproteins: (i) the low density lipoprotein (LDL) receptor and (ii) the chylomicron remnant receptor. In homozygous Watanabe-heritable hyperlipidemic (WHHL) rabbits, an animal model for human familial hypercholesterolemia, LDL rec...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kita, T, Brown, M S, Bilheimer, D W, Goldstein, J L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6957885/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.18.5693
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