Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats

Glycemic regulation improves myocardial function in diabetic patients, but finding optimal therapeutic strategies remains challenging. Recent data have shown that pharmacological inhibition of soluble epoxide hydrolase (sEH), an enzyme that decreases the endogenous levels of protective epoxyeicosatr...

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Main Authors: Guglielmino, Kathleen, Jackson, Kaleena, Harris, Todd R., Vu, Vincent, Dong, Hua, Dutrow, Gavin, Evans, James E., Graham, James, Cummings, Bethany P., Havel, Peter J., Chiamvimonvat, Nipavan, Despa, Sanda, Hammock, Bruce D., Despa, Florin
格式: Artigo
語言:Inglês
出版: American Physiological Society 2012
主題:
Energetics and Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469704/
https://ncbi.nlm.nih.gov/pubmed/22865388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00154.2012
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