Loss of MLK3 signaling impedes ulcer healing by modulating MAPK signaling in mouse intestinal mucosa

Mixed-lineage kinase 3 (MLK3) activates multiple MAPK pathways and can initiate apoptosis, proliferation, migration, or differentiation in different cell types. However, whether MLK3 signaling regulates intestinal epithelial cell sheet migration in vivo is not known. We sought to investigate whether...

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Bibliografiske detaljer
Main Authors: Kovalenko, Pavlo L., Kunovska, Lyudmyla, Chen, Jian, Gallo, Kathleen A., Basson, Marc D.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Mucosal Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469692/
https://ncbi.nlm.nih.gov/pubmed/22917630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00158.2012
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