Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling

Kallistatin (KS) levels are reduced in the kidney and blood vessels under oxidative stress conditions. To determine the function of endogenous KS in the renal and cardiovascular systems, KS levels were depleted by daily injection of anti-rat KS antibody into DOCA-salt hypertensive rats for 10 days....

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Bibliographic Details
Main Authors: Liu, Yuying, Bledsoe, Grant, Hagiwara, Makato, Shen, Bo, Chao, Lee, Chao, Julie
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469672/
https://ncbi.nlm.nih.gov/pubmed/22811485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00257.2012
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