Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system

ANG II-stimulated production of reactive oxygen species (ROS) through NADPH oxidase is suggested to activate MAPK pathways, which are implicated in neurally mediated pressor effects of ANG II. Emerging evidence suggests that ANG-(1–7) up regulates MAPK phosphatases to reduce MAPK signaling and atten...

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Detalhes bibliográficos
Main Authors: Nautiyal, Manisha, Katakam, Prasad V. G., Busija, David W., Gallagher, Patricia E., Tallant, E. Ann, Chappell, Mark C., Diz, Debra I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Neural Control
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469665/
https://ncbi.nlm.nih.gov/pubmed/22914751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00566.2011
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