Long-term systemic angiotensin II type 1 receptor blockade regulates mRNA expression of dorsomedial medulla renin-angiotensin system components

In Fischer 344 (F344) rats, renin-angiotensin system (RAS) blockade for 1 yr with the angiotensin II type 1 (AT(1)) receptor blocker L-158,809 prevents age-related impairments in metabolic function, similar to transgenic rats with low glial angiotensinogen (Aogen). Brain RAS regulation may contribut...

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Main Authors: Gilliam-Davis, Shea, Gallagher, Patricia E., Payne, Valerie S., Kasper, Sherry O., Tommasi, Ellen N., Westwood, Brian M., Robbins, Michael E., Chappell, Mark C., Diz, Debra I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132839/
https://ncbi.nlm.nih.gov/pubmed/21540301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00167.2010
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