Scavenger Receptor Class A Plays a Central Role in Mediating Mortality and the Development of the Pro-Inflammatory Phenotype in Polymicrobial Sepsis

Sepsis is a frequent complication in critical illness. The mechanisms that are involved in initiation and propagation of the disease are not well understood. Scavenger receptor A (SRA) is a membrane receptor that binds multiple polyanions such as oxidized LDL and endotoxin. Recent studies suggest th...

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Autors principals: Ozment, Tammy R., Ha, Tuanzhu, Breuel, Kevin F., Ford, Tiffany R., Ferguson, Donald A., Kalbfleisch, John, Schweitzer, John B., Kelley, Jim L., Li, Chuanfu, Williams, David L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469655/
https://ncbi.nlm.nih.gov/pubmed/23071440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002967
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