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Pms2 Suppresses Large Expansions of the (GAA·TTC)(n) Sequence in Neuronal Tissues
Expanded trinucleotide repeat sequences are the cause of several inherited neurodegenerative diseases. Disease pathogenesis is correlated with several features of somatic instability of these sequences, including further large expansions in postmitotic tissues. The presence of somatic expansions in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469490/ https://ncbi.nlm.nih.gov/pubmed/23071719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047085 |
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