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Use of Pleiotropy to Model Genetic Interactions in a Population

Systems-level genetic studies in humans and model systems increasingly involve both high-resolution genotyping and multi-dimensional quantitative phenotyping. We present a novel method to infer and interpret genetic interactions that exploits the complementary information in multiple phenotypes. We...

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Détails bibliographiques
Auteurs principaux: Carter, Gregory W., Hays, Michelle, Sherman, Amir, Galitski, Timothy
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469415/
https://ncbi.nlm.nih.gov/pubmed/23071457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003010
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