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PREDICTING THE EFFECTS OF COPY-NUMBER VARIATION IN DOUBLE AND TRIPLE MUTANT COMBINATIONS

The study of genetic interactions is a powerful tool in inferring structure and function of biological networks. To date, genetic interaction studies have been dominated by pair-wise gene deletion screens. However, classical genetic analysis and natural genetic variation involve diverse gene forms r...

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Detalhes bibliográficos
Main Authors: Carter, Gregory W., Hays, Michelle, Li, Song, Galitski, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334851/
https://ncbi.nlm.nih.gov/pubmed/22174259
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