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Activation of Peripheral P2X Receptors is Sufficient to Induce Central Sensitization in Rat Medullary Dorsal Horn Nociceptive Neurons

Central sensitization and purinergic receptor mechanisms have been implicated as important processes in acute and chronic pain conditions following injury or inflammation of peripheral tissues. This study has documented that application of the P2X(1,2/3,3) receptor agonist αß-meATP (100 mM) to the r...

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Hlavní autoři: Cherkas, Pavel S., Dostrovsky, Jonathan O., Sessle, Barry J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469263/
https://ncbi.nlm.nih.gov/pubmed/22910609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.007
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