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The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds
The heat shock transcription factor HSF1 governs the response to heat shock, oxidative stresses, and xenobiotics through unknown mechanisms. We demonstrate that diverse thiol-reactive molecules potently activate budding yeast Hsf1. Hsf1 activation by thiol-reactive compounds is not consistent with t...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469052/ https://ncbi.nlm.nih.gov/pubmed/22809627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-06-0447 |
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