A small hypervariable segment in the variable domain of an immunoglobulin light chain stimulates formation of anti-idiotypic suppressor T cells.

The induction in BALB/c mice of suppressor T cells that block a delayed-type hypersensitivity (DTH) response to the idiotype of M315, a myeloma protein of BALB/c origin, was examined with a variety of immunoglobulin chains and fragments whose amino acid sequences are known. Normal BALB/c mice receiv...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Sakato, N, Semma, M, Eisen, H N, Azuma, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1982
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6215651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.17.5396
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