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A small hypervariable segment in the variable domain of an immunoglobulin light chain stimulates formation of anti-idiotypic suppressor T cells.
The induction in BALB/c mice of suppressor T cells that block a delayed-type hypersensitivity (DTH) response to the idiotype of M315, a myeloma protein of BALB/c origin, was examined with a variety of immunoglobulin chains and fragments whose amino acid sequences are known. Normal BALB/c mice receiv...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC346904/ https://ncbi.nlm.nih.gov/pubmed/6215651 |
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