The Changes in MGMT Promoter Methylation Status in Initial and Recurrent Glioblastomas

To evaluate the mechanism of the development of therapeutic resistance after temozolomide treatment, we focused on changes in O(6)-methylguanine DNA methyltransferase (MGMT) and mismatch repair (MMR) between initial and recurrent glioblastomas. Tissue samples obtained from 24 paired histologically c...

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Detalhes bibliográficos
Main Authors: Park, Chul-Kee, Kim, Ja Eun, Kim, Ji Young, Song, Sang Woo, Kim, Jin Wook, Choi, Seung Hong, Kim, Tae Min, Lee, Se-Hoon, Kim, Il Han, Park, Sung-Hye
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468928/
https://ncbi.nlm.nih.gov/pubmed/23066447
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