Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients

Pseudoprogression is a major diagnostic dilemma in current treatment protocols for malignant gliomas that involve concurrent chemoradiotherapy. We hypothesized that methylation-specific multiplex ligation probe amplification (MS-MLPA), an assay that permits semiquantitative evaluation of promoter me...

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Detalhes bibliográficos
Main Authors: Park, Chul-Kee, Kim, JinWook, Yim, Su Youn, Lee, Ah Reum, Han, Jung Ho, Kim, Chae-Yong, Park, Sung-Hye, Kim, Tae Min, Lee, Se-Hoon, Choi, Seung Hong, Kim, Seung-Ki, Kim, Dong Gyu, Jung, Hee-Won
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064622/
https://ncbi.nlm.nih.gov/pubmed/21075779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq162
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