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Growth conditions and environmental factors impact aerosolization but not virulence of Francisella tularensis infection in mice

In refining methodology to develop a mouse model for inhalation of Francisella tularensis, it was noted that both relative humidity and growth media impacted the aerosol concentration of the live vaccine strain (LVS) of F. tularensis. A relative humidity of less than 55% had a negative impact on the...

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Autori principali: Faith, Seth A., Smith, Le'Kneitah P., Swatland, Angela S., Reed, Douglas S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468843/
https://ncbi.nlm.nih.gov/pubmed/23087911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2012.00126
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