Live Attenuated Mutants of Francisella tularensis Protect Rabbits against Aerosol Challenge with a Virulent Type A Strain

Francisella tularensis, a Gram-negative bacterium, is the causative agent of tularemia. No licensed vaccine is currently available for protection against tularemia, although an attenuated strain, dubbed the live vaccine strain (LVS), is given to at-risk laboratory personnel as an investigational new...

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Detalhes bibliográficos
Main Authors: Reed, Douglas S., Smith, Le'Kneitah P., Cole, Kelly Stefano, Santiago, Araceli E., Mann, Barbara J., Barry, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993426/
https://ncbi.nlm.nih.gov/pubmed/24614653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01498-14
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