Heat shock factor 1 is inactivated by amino acid deprivation

Mammalian cells respond to a lack of amino acids by activating a transcriptional program with the transcription factor ATF4 as one of the main actors. When cells are faced with cytoplasmic proteotoxic stress, a quite different transcriptional response is mounted, the heat shock response, which is me...

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Bibliografiske detaljer
Main Authors: Hensen, Sanne M. M., Heldens, Lonneke, van Enckevort, Chrissy M. W., van Genesen, Siebe T., Pruijn, Ger J. M., Lubsen, Nicolette H.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2012
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468675/
https://ncbi.nlm.nih.gov/pubmed/22797943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0347-1
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