Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells.

UT-1 cells are a clone of Chinese hamster ovary cells that were selected to grow in the presence of compactin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase [mevalonate: NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34]. These cells have 100- to 1,000-fold more immunopr...

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Main Authors: Faust, J R, Luskey, K L, Chin, D J, Goldstein, J L, Brown, M S
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC346864/
https://ncbi.nlm.nih.gov/pubmed/6957860
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