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Activating Nrf-2 Signaling Depresses Unilateral Ureteral Obstruction-Evoked Mitochondrial Stress-Related Autophagy, Apoptosis and Pyroptosis in Kidney

Exacerbated oxidative stress and inflammation may induce three types of programmed cell death, autophagy, apoptosis and pyroptosis in unilateral ureteral obstruction (UUO) kidney. Sulforaphane activating NF-E2-related nuclear factor erythroid-2 (Nrf-2) signaling may ameliorate UUO-induced renal dama...

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Detalhes bibliográficos
Main Authors: Chung, Shue Dong, Lai, Ting Yu, Chien, Chiang Ting, Yu, Hong Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468574/
https://ncbi.nlm.nih.gov/pubmed/23071780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047299
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