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Pathways Involved in the Synergistic Activation of Macrophages by Lipoteichoic Acid and Hemoglobin

Lipoteichoic acid (LTA) is a Gram-positive cell surface molecule that is found in both a cell-bound form and cell-free form in the host during an infection. Hemoglobin (Hb) can synergize with LTA, a TLR2 ligand, to potently activate macrophage innate immune responses in a TLR2- and TLR4-dependent wa...

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Autors principals: Cox, Kathleen H., Cox, Michelle E., Woo-Rasberry, Virginia, Hasty, David L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468568/
https://ncbi.nlm.nih.gov/pubmed/23071790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047333
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