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Pathways Involved in the Synergistic Activation of Macrophages by Lipoteichoic Acid and Hemoglobin
Lipoteichoic acid (LTA) is a Gram-positive cell surface molecule that is found in both a cell-bound form and cell-free form in the host during an infection. Hemoglobin (Hb) can synergize with LTA, a TLR2 ligand, to potently activate macrophage innate immune responses in a TLR2- and TLR4-dependent wa...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468568/ https://ncbi.nlm.nih.gov/pubmed/23071790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047333 |
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