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Removal of O6-methylguanine from DNA by human liver fractions.
In in vitro assays using methylated DNAs as substrates, human liver fractions were shown to be able to catalyze the removal of O6-methylguanine. The amount of removal was proportional to the amount of protein added, and the loss of O6-methylguanine occurred with stoichiometric formation of guanine i...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6957855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.17.5162 |
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