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Removal of O6-methylguanine from DNA by human liver fractions.

In in vitro assays using methylated DNAs as substrates, human liver fractions were shown to be able to catalyze the removal of O6-methylguanine. The amount of removal was proportional to the amount of protein added, and the loss of O6-methylguanine occurred with stoichiometric formation of guanine i...

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Détails bibliographiques
Auteurs principaux: Pegg, A E, Roberfroid, M, von Bahr, C, Foote, R S, Mitra, S, Bresil, H, Likhachev, A, Montesano, R
Format: Artigo
Langue:Inglês
Publié: 1982
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC346854/
https://ncbi.nlm.nih.gov/pubmed/6957855
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