Activin B regulates islet composition and islet mass but not whole body glucose homeostasis or insulin sensitivity

Based on the phenotype of the activin-like kinase-7 (ALK7)-null mouse, activins A and B have been proposed to play distinct roles in regulating pancreatic islet function and glucose homeostasis, with activin A acting to enhance islet function and insulin release while activin B antagonizes these act...

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Bibliografiske detaljer
Main Authors: Bonomi, Lara, Brown, Melissa, Ungerleider, Nathan, Muse, Meghan, Matzuk, Martin M., Schneyer, Alan
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468507/
https://ncbi.nlm.nih.gov/pubmed/22739106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00177.2012
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