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Differential synthesis and action of TGFβ superfamily ligands in mouse and rat islets
Members of the TGFβ superfamily, including activins and TGFβ, modulate glucose-stimulated insulin secretion (GSIS) in vitro using rat islets while genetic manipulations that reduce TGFβ superfamily signaling in vivo in mice produced hypoplastic islets and/or hyperglycemia. Moreover, deletion of Fstl...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329517/ https://ncbi.nlm.nih.gov/pubmed/21964310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.3.6.18013 |
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