HSP47 regulates ECM accumulation in renal proximal tubular cells induced by TGF-β(1) through ERK1/2 and JNK MAPK pathways

Heat shock protein (HSP)47 is a collagen-specific molecular chaperone that is essential for the biosynthesis of collagen molecules. It is likely that increased levels of HSP47 contribute to the assembly of procollagen and thereby cause an excessive accumulation of collagens in disease processes asso...

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Hong-bo, Liu, Rui-hong, Ling, Guang-hui, Xiao, Li, Xia, Yuan-chen, Liu, Fu-you, Li, Jun, Liu, Ying-hong, Chen, Qin-kai, Lv, Jin-lei, Zhan, Ming, Yang, Shi-kun, Kanwar, Yashpal S., Sun, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468491/
https://ncbi.nlm.nih.gov/pubmed/22718885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00470.2011
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