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HSP47 regulates ECM accumulation in renal proximal tubular cells induced by TGF-β(1) through ERK1/2 and JNK MAPK pathways
Heat shock protein (HSP)47 is a collagen-specific molecular chaperone that is essential for the biosynthesis of collagen molecules. It is likely that increased levels of HSP47 contribute to the assembly of procollagen and thereby cause an excessive accumulation of collagens in disease processes asso...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468491/ https://ncbi.nlm.nih.gov/pubmed/22718885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00470.2011 |
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