Interferon-γ ablation exacerbates myocardial hypertrophy in diastolic heart failure

Diastolic heart failure (HF) accounts for up to 50% of all HF admissions, with hypertension being the major cause of diastolic HF. Hypertension is characterized by left ventricular (LV) hypertrophy (LVH). Proinflammatory cytokines are increased in LVH and hypertension, but it is unknown if they medi...

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Autores principales: Garcia, Anthony G., Wilson, Richard M., Heo, Joline, Murthy, Namita R., Baid, Simoni, Ouchi, Noriyuki, Sam, Flora
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
Materias:
Integrative Cardiovascular Physiology and Pathophysiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468473/
https://ncbi.nlm.nih.gov/pubmed/22730392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00298.2012
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