Adaptive resynthesis of O(6)-methylguanine-accepting protein can explain the differences between mammalian cells proficient and deficient in methyl excision repair
Mammalian cells have been classified as proficient (Mer(+)) or deficient (Mer(-)) in methyl excision repair in terms of their cytotoxic reactions to agents that form O(6)-alkylguanine and their abilities to reactivate alkylated adenoviruses. O(6)-Methylguanine (O(6)MeGua) is considered to be a letha...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6957853/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.17.5117 |
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