AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

Innate lymphoid cells (ILC)-22 protect the intestinal mucosa from infections by secreting interleukin-22 (IL-22). They include NKp46(+) and Lymphoid Tissues inducer (LTi)-like subsets. Both express the aryl-hydrocarbon receptor (AHR), a sensor for environmental, dietary and endogenous aromatic compo...

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Detalhes bibliográficos
Main Authors: Lee, Jacob, Cella, Marina, McDonald, Keely, Garlanda, Cecilia, Kennedy, Gregory D., Nukaya, Manabu, Mantovani, Alberto, Kopan, Raphael, Bradfield, Christopher A., Newberry, Rodney, Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468413/
https://ncbi.nlm.nih.gov/pubmed/22101730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2187
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