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The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective

The Wnt signaling pathway was initially discovered for its role in tumorigenesis and the development of Drosophila and other eukaryotic organisms. The key effector of this pathway, the bipartite transcription factor β-cat/TCF, is formed by free β-catenin (β-cat) and a TCF protein, including TCF7L2....

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Главные авторы: Ip, Wilfred, Chiang, Yu-ting Alex, Jin, Tianru
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468386/
https://ncbi.nlm.nih.gov/pubmed/22892353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-2-28
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