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Vitamin D receptor activation and downregulation of renin-angiotensin system attenuate morphine-induced T cell apoptosis

Opiates have been reported to induce T cell loss. We evaluated the role of vitamin D receptor (VDR) and the activation of the renin-angiotensin system (RAS) in morphine-induced T cell loss. Morphine-treated human T cells displayed downregulation of VDR and the activation of the RAS. On the other han...

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Detalhes bibliográficos
Main Authors: Chandel, Nirupama, Sharma, Bipin, Salhan, Divya, Husain, Mohammad, Malhotra, Ashwani, Buch, Shilpa, Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468348/
https://ncbi.nlm.nih.gov/pubmed/22763121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00076.2012
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