Glucocorticoids increase the Na+-H+ exchange and decrease the Na+ gradient-dependent phosphate-uptake systems in renal brush border membrane vesicles.

The glucocorticoid dexamethasone, but not the mineralocorticoid aldosterone, increased amiloride-sensitive Na+-H+ exchange activity in rat proximal tubule brush border vesicles. Na+ uptake, independent of amiloride, was not affected. The glucocorticoid decreased the Na+ gradient-dependent phosphate...

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Main Authors: Freiberg, J M, Kinsella, J, Sacktor, B
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC346799/
https://ncbi.nlm.nih.gov/pubmed/6956901
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