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Glucocorticoids increase the Na+-H+ exchange and decrease the Na+ gradient-dependent phosphate-uptake systems in renal brush border membrane vesicles.

The glucocorticoid dexamethasone, but not the mineralocorticoid aldosterone, increased amiloride-sensitive Na+-H+ exchange activity in rat proximal tubule brush border vesicles. Na+ uptake, independent of amiloride, was not affected. The glucocorticoid decreased the Na+ gradient-dependent phosphate...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Freiberg, J M, Kinsella, J, Sacktor, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6956901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.16.4932
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