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Inhibition of hepatic cholesterol synthesis in mice by sterols with shortened and stereochemically varied side chains.

Mice were fed cholesterol or various other sterols for 26 hr, after which the amount of hepatic cholesterol synthesis was measured in a cell-free system. The following sterols were as effective as cholesterol itself in depressing the conversion of acetate into sterol: pregn-5-en-3 beta-ol, which lac...

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Bibliografiske detaljer
Main Authors: Erickson, K A, Nes, W R
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC346787/
https://ncbi.nlm.nih.gov/pubmed/6289321
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