Opiate antagonistic properties of an octapeptide somatostatin analog.

The somatostatin analog D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-NH-CH(CH2OH)CHOHCH3 (SMS 201-995) displaces [3h[naloxone from its binding sites (IC50, 38 +/- 60 nM), being more than 200 times more potent than somatostatin. As measured by the difference between [3H]dihydromorphine, [3H][D-Ala2,D-Leu5]enkepha...

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में प्रकाशित:	Proc Natl Acad Sci U S A
मुख्य लेखकों:	Maurer, R, Gaehwiler, B H, Buescher, H H, Hill, R C, Roemer, D
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	National Academy of Sciences 1982
विषय:	Research Article
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6126877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.15.4815
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