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Synthesis and biological activity of highly potent octapeptide analogs of somatostatin.
In the search for selective and long-acting analogs of somatostatin, nearly 200 compounds were synthesized by solid-phase methods, purified, and tested biologically. Among these octapeptides, some contained N-terminal (Formula: see text) were 177 times and 113 times more potent, respectively, than s...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1986
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2869490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1896 |
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