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Synthesis and biological activity of highly potent octapeptide analogs of somatostatin.

In the search for selective and long-acting analogs of somatostatin, nearly 200 compounds were synthesized by solid-phase methods, purified, and tested biologically. Among these octapeptides, some contained N-terminal (Formula: see text) were 177 times and 113 times more potent, respectively, than s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cai, R Z, Szoke, B, Lu, R, Fu, D, Redding, T W, Schally, A V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC323191/
https://ncbi.nlm.nih.gov/pubmed/2869490
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