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Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis.

The nonimmunogenic thymic leukemia TH, obtained in mouse strain CBA/Ht, was adapted to culture. By in vitro treatment of a clonal TH cell line with the mutagen N-methyl-N'-nitro-N-nitrosoguanidine, stable variant cell clones (tum-) were obtained that elicited a rejection response in syngeneic m...

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Detalhes bibliográficos
Main Authors: Van Pel, A, Boon, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC346748/
https://ncbi.nlm.nih.gov/pubmed/6981814
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