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Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis.
The nonimmunogenic thymic leukemia TH, obtained in mouse strain CBA/Ht, was adapted to culture. By in vitro treatment of a clonal TH cell line with the mutagen N-methyl-N'-nitro-N-nitrosoguanidine, stable variant cell clones (tum-) were obtained that elicited a rejection response in syngeneic m...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6981814/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.15.4718 |
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