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The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis
Activation of muscle-specific genes by members of the myocyte enhancer factor 2 (MEF2) and MyoD families of transcription factors is coupled to histone acetylation and is inhibited by class II histone deacetylases (HDACs) 4 and 5, which interact with MEF2. The ability of HDAC4 and -5 to inhibit MEF2...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC34672/ https://ncbi.nlm.nih.gov/pubmed/11390982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131198498 |
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