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The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis

Activation of muscle-specific genes by members of the myocyte enhancer factor 2 (MEF2) and MyoD families of transcription factors is coupled to histone acetylation and is inhibited by class II histone deacetylases (HDACs) 4 and 5, which interact with MEF2. The ability of HDAC4 and -5 to inhibit MEF2...

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Autors principals: Zhang, Chun Li, McKinsey, Timothy A., Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC34672/
https://ncbi.nlm.nih.gov/pubmed/11390982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131198498
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