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Slc11a1 limits intracellular growth of Salmonella enterica sv. Typhimurium by promoting macrophage immune effector functions and impairing bacterial iron acquisition

The natural-resistance associated macrophage protein 1, Slc11a1, is a phagolysosomal transporter for protons and divalent ions including iron, that confers host protection against diverse intracellular pathogens including Salmonella. We investigated and compared the regulation of iron homeostasis an...

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Detalhes bibliográficos
Main Authors: Nairz, Manfred, Fritsche, Gernot, Crouch, Marie-Laure V., Barton, Howard C., Fang, Ferric C., Weiss, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467104/
https://ncbi.nlm.nih.gov/pubmed/19500110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2009.01337.x
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