Kinetics of endogenous mouse FEN1 in base excision repair

The structure specific flap endonuclease 1 (FEN1) plays an essential role in long-patch base excision repair (BER) and in DNA replication. We have generated a fluorescently tagged FEN1 expressing mouse which allows monitoring the localization and kinetics of FEN1 in response to DNA damage in living...

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Bibliographische Detailangaben
Hauptverfasser: Kleppa, Liv, Mari, Pierre-Olivier, Larsen, Elisabeth, Lien, Guro Flor, Godon, Camille, Theil, Arjan F., Nesse, Gaute J., Wiksen, Hege, Vermeulen, Wim, Giglia-Mari, Giuseppina, Klungland, Arne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467068/
https://ncbi.nlm.nih.gov/pubmed/22810208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks673
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