Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme

Bacterial spores possess an enormous resistance to ultraviolet (UV) radiation. This is largely due to a unique DNA repair enzyme, Spore Photoproduct Lyase (SP lyase) that repairs a specific UV-induced DNA lesion, the spore photoproduct (SP), through an unprecedented radical-based mechanism. Unlike D...

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Detalhes bibliográficos
Main Authors: Benjdia, Alhosna, Heil, Korbinian, Barends, Thomas R. M., Carell, Thomas, Schlichting, Ilme
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467042/
https://ncbi.nlm.nih.gov/pubmed/22761404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks603
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