Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice

Inhibition of leukocyte adhesion to the vascular endothelium represents a novel and important approach for decreasing sickle cell disease (SCD) vaso-occlusion. Using a humanized SCD–mouse-model of tumor necrosis factor-α–induced acute vaso-occlusion, we herein present data demonstrating that short-t...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Almeida, Camila Bononi, Scheiermann, Christoph, Jang, Jung-Eun, Prophete, Colette, Costa, Fernando Ferreira, Conran, Nicola, Frenette, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2012
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466969/
https://ncbi.nlm.nih.gov/pubmed/22833547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409524
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares